RAF265

• Target :

  VEGFR|||Apoptosis|||Raf|||Autophagy

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Apoptosis|||Angiogenesis|||Autophagy|||MAPK

• Purity :

  0.9956

• Bioactivity :

  RAF265 (CHIR-265) (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM. Phase 2.

• Smiles :

  Cn1c(Nc2ccc(cc2)C(F)(F)F)nc2cc(Oc3ccnc(c3)-c3ncc([nH]3)C(F)(F)F)ccc12

• Molecular Formula :

  C24H16F6N6O

• Molecular Weight :

  518.41

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  927880-90-8