RAF265

• Target:

  VEGFR|||Apoptosis|||Raf|||Autophagy

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Apoptosis|||Angiogenesis|||Autophagy|||MAPK

• Purity:

  0.9956

• Bioactivity:

  RAF265 (CHIR-265) (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM. Phase 2.

• Smiles:

  Cn1c (Nc2ccc (cc2) C (F) (F) F) nc2cc (Oc3ccnc (c3) -c3ncc ([nH]3) C (F) (F) F) ccc12

• Molecular Formula:

  C24H16F6N6O

• Molecular Weight:

  518.41

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  927880-90-8