AMXI-5001

• Target :

  Others|||Microtubule Associated

• Related Pathways :

  Cytoskeletal Signaling|||Others

• Bioactivity :

  AMXI-5001 is a potent, orally active inhibitor of PARP1/2 and microtubule aggregation. AMXI-5001 shows selective anti-tumor cytotoxicity against a wide range of human cancer cells with IC50s well below those of existing clinical PARP1/2 inhibitors and induces complete regression of established tumors, including very large ones.

• Smiles :

  CCOC(=O)Nc1nc2ccc(cc2[nH]1)-c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F

• Molecular Formula :

  C25H20FN5O3

• Molecular Weight :

  457.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2170491-77-5