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AMXI-5001

CAT: 0931-T62847-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62847-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2170491-77-5
Target
Others, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
AMXI-5001 is a potent, orally active inhibitor of PARP1/2 and microtubule aggregation. AMXI-5001 shows selective anti-tumor cytotoxicity against a wide range of human cancer cells with IC50s well below those of existing clinical PARP1/2 inhibitors and induces complete regression of established tumors, including very large ones.
Smiles
CCOC(=O)Nc1nc2ccc(cc2[nH]1)-c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F
Molecular Formula
C25H20FN5O3
Molecular Weight
457.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C