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Tinlorafenib

CAT: 0931-T62841-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62841-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2573781-75-4
Target
Raf, Others, ERK
Related Pathways
Others, MAPK
Bioactivity
Tinlorafenib (PF-07284890) (compound 10) is an orally active, central nervous system (CNS) -permeable BRAF kinase inhibitor targeting BRAFV600E (IC50: 4.25 nM) and V600K (IC50: 2.7 nM) . Tinlorafenib is applicable for studying BRAF-associated malignant and benign tumors of the CNS and extracranial malignancies.
Smiles
CC1=C2C(=CC=C1NC3=C(Cl)C(NS(CCCF)(=O)=O)=CC=C3F)N=CN(C)C2=O
Molecular Formula
C19H19ClF2N4O3S
Molecular Weight
456.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
C01799-01Tinlorafenib

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