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LY487379

CAT: 0931-T62756Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T62756Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
353231-17-1
Target
Others, GluR
Related Pathways
Others, Neuroscience
Bioactivity
LY487379 is a selective human mGluR2 positive allosteric modulator (PAM) that enhances glutamate-stimulated [35 S] GTPγS binding to mGlu2 receptors (EC50: 1.7 μM) and mGlu3 receptors (EC50 >10 μM) . LY487379 induces cognitive flexibility and behavioral inhibition in a rat model and can be used to study schizophrenia.
Smiles
COc1ccccc1Oc1ccc(cc1)N(Cc1cccnc1)S(=O)(=O)CC(F)(F)F
Molecular Formula
C21H19F3N2O4S
Molecular Weight
452.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
BA5574-25LY487379
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HY-103552-01LY487379 (hydrochloride)
GTR19201151LY487379 hydrochloride

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