(R) -MLT-985

• Target:

  MALT|||Others

• Related Pathways:

  Others|||Immunology/Inflammation

• Bioactivity:

  (R) -MLT-985 (compound 11) is a potent MALT1 protease inhibitor (IC50: 3 nM) and has an IC50 value of 20 nM for MALT1-dependent IL-2 in Jurkat cells. Additionally, (R) -MLT-985 inhibits the growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells.

• Smiles:

  [C@@H](OC)(C)C=1N2C(N=CC1NC(NC=3C=C(Cl)C(=NC3)N4N=CC=N4)=O)=CC(Cl)=N2

• Molecular Formula:

  C17H15Cl2N9O2

• Molecular Weight:

  448.27

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1832577-07-7