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(R) -MLT-985

CAT: 0931-T62680-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62680-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1832577-07-7
Target
MALT, Others
Related Pathways
Others, Immunology/Inflammation
Bioactivity
(R) -MLT-985 (compound 11) is a potent MALT1 protease inhibitor (IC50: 3 nM) and has an IC50 value of 20 nM for MALT1-dependent IL-2 in Jurkat cells. Additionally, (R) -MLT-985 inhibits the growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells.
Smiles
[C@@H](OC)(C)C=1N2C(N=CC1NC(NC=3C=C(Cl)C(=NC3)N4N=CC=N4)=O)=CC(Cl)=N2
Molecular Formula
C17H15Cl2N9O2
Molecular Weight
448.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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