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Ganaplacide hydrochloride

CAT: 0931-T62677-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T62677-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2751586-94-2
Target
PI4K, Parasite, Antibiotic
Related Pathways
Microbiology/Virology, PI3K/Akt/mTOR signaling
Purity
0.9397
Bioactivity
Ganaplacide hydrochloride (KAF156 HCl) is an orally administered imidazopyrimidine antimalarial agent that inhibits Plasmodium PI4K activity. It exhibits activity against Plasmodium falciparum, Plasmodium vivax, and artemisinin-resistant parasites, including artemisinin-resistant strains, and exerts effects during both the blood and liver stages.
Smiles
Cl.O=C(N1CCN2C(=NC(C3=CC=C(F)C=C3)=C2NC4=CC=C(F)C=C4)C1(C)C)CN
Molecular Formula
C22H24ClF2N5O
Molecular Weight
447.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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