Products for Research Use Only

SPH3127

CAT: 0931-T62618-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T62618-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1399849-02-5
Target
Others, RAAS
Related Pathways
Others, Endocrinology/Hormones
Bioactivity
SPH3127 (DRI 18) is a potent, orally active, novel direct renin inhibitor with IC50 values of 0.4 nM for recombinant human-renin and 0.45 nM for human plasma renin activity. SPH3127 has an anti-hypertensive effect and can be used to study hypertension.
Smiles
[C@@H](N(C(=O)[C@H]1CNCCO1)C2CC2)(C)C=3C=4C(N(CCCNC(OC)=O)N3)=NC(C)=CC4
Molecular Formula
C22H32N6O4
Molecular Weight
444.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products