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INCB38579

CAT: 0931-T62460-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62460-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1246207-65-7
Target
Histamine Receptor, Others
Related Pathways
Neuroscience, Others, Immunology/Inflammation, GPCR/G Protein
Bioactivity
INCB38579 is a selective, orally active, histamine H4 receptor (HH4R) antagonist that crosses the blood-brain barrier and acts on hH4R (IC50: 4.8 nM), mH4R (IC50: 42 nM), and rH4R (IC50: 32 nM) . INCB38579 has anti-inflammatory and antipruritic effects.
Smiles
CN1CCN(CC1)c1cc(nc(N)n1)-c1ccc2CCN(Cc2c1)C(=O)CC1CCCC1
Molecular Formula
C25H34N6O
Molecular Weight
434.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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