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Irinotecan

CAT: 0931-T6228-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T6228-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
97682-44-5
Target
Topoisomerase, Autophagy
Related Pathways
Autophagy, DNA Damage/DNA Repair
Purity
>99.99%
Bioactivity
Irinotecan (CPT-11), a derivative of camptothecin, is an inhibitor of DNA topoisomerase I (Topo I) . Irinotecan has antitumor activity by preventing DNA strand reattachment through binding to the Topo I complex, resulting in double-stranded DNA breaks and cell death.
Smiles
CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OC(=O)N3CCC(CC3)N3CCCCC3)cc12
Molecular Formula
C33H38N4O6
Molecular Weight
586.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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