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Selumetinib

CAT: 0931-T6218-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T6218-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
606143-52-6
Target
ERK, MEK, Apoptosis
Related Pathways
MAPK, Apoptosis
Purity
0.999
Bioactivity
Selumetinib (AZD6244) is a MEK1/2 inhibitor that inhibits MEK1 (IC50=14 nM) with potent selectivity and is non-ATP-competitive. Selumetinib has antitumor activity and is used for the treatment of neurofibromatosis type 1 (NF1) .
Smiles
CN1C=NC2=C(F)C(NC3=CC=C(Br)C=C3Cl)=C(C=C12)C(=O)NOCCO
Molecular Formula
C17H15BrClFN4O3
Molecular Weight
457.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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