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GSK3494245

CAT: 0931-T62080-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62080-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2080410-41-7
Target
Parasite, Proteasome, Others
Related Pathways
Ubiquitination, Microbiology/Virology, Others, Proteases/Proteasome
Purity
0.9585
Bioactivity
GSK3494245 (DDD01305143) is a potent, selective, orally active inhibitor of chymotrypsin-like activity that binds to the proteasome of WTL.donovani (IC50: 0.16 μM), sandwiched between the β4 and β5 subunits, exhibiting good biosafety properties and suitability for inhibiting chymotrypsin-like activity of the human proteasome (IC50: 26S=13 μM; enriched THP-1 extract IC50=40 μM) .
Smiles
Fc1ccc(NC(=O)N2CCCC2)cc1-c1ccn2c(cnc2n1)N1CCOCC1
Molecular Formula
C21H23FN6O2
Molecular Weight
410.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA2139-5.1GSK3494245

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