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LPM4870108

CAT: 0931-T62076-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62076-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, Trk receptor
Related Pathways
Others, Tyrosine Kinase/Adaptors
Bioactivity
LPM4870108 is a potent, orally active pan-Trk (WT/MT) inhibitor that acts on TrkC (IC50: 0.2 nM), TrkA (IC50: 2.4 nM), TrkAG595R (IC50: 3.5 nM) and TrkAG667C (IC50: 2.3 nM), and is more selective for Trk than ALK (IC50: 2.3 nM) . LPM4870108 showed anti-tumour effects.
Molecular Formula
C20H19FN6O3
Molecular Weight
410.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-132229LPM4870108

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