Evogliptin

• Target:

  Proteasome|||Autophagy|||Others

• Related Pathways:

  Proteases/Proteasome|||Ubiquitination|||Others|||Autophagy

• Bioactivity:

  Evogliptin (DA-1229) is a DPP4 inhibitor with oral activity. Evogliptin has significant and lasting hypoglycemic effect in mouse model. Evogliptin inhibits the production of the fibrosis and inflammatory in hepatocytes signals by inducing autophagy. Evogliptin can be used to study type 2 diabetes, chronic liver inflammation, osteoporosis and renal impairment.

• Smiles:

  C(C[C@@H](CC1=C(F)C=C(F)C(F)=C1)N)(=O)N2[C@H](COC(C)(C)C)C(=O)NCC2

• Molecular Formula:

  C19H26F3N3O3

• Molecular Weight:

  401.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1222102-29-5