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HGGPPS-IN-1

CAT: 0931-T61945-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61945-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1429012-38-3
Target
Others, Apoptosis
Related Pathways
Others, Apoptosis
Bioactivity
HGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs) . HGGPPS-IN-1 has an effective inhibitory effect on human geranyl geranyl pyrophosphate synthase (hGGPPS) . HGGPPS-IN-1 can selectively induce apoptosis of multiple myeloma (MM) cells. HGGPPS-IN-1 showed anti-myeloma activity in vivo.
Smiles
N(C(P(=O)(O)O)P(=O)(O)O)C1=C2C(=NC(=N1)C3=CC=CC=C3)SC=C2
Molecular Formula
C13H13N3O6P2S
Molecular Weight
401.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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