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Mirdametinib

CAT: 0931-T6189-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T6189-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
391210-10-9
Target
Autophagy, MEK, Apoptosis
Related Pathways
Apoptosis, MAPK, Autophagy
Purity
0.9991
Bioactivity
Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity. Mirdametinib exhibits antitumor activity by inhibiting p-ERK1/2 expression and inducing apoptosis.
Smiles
OC[C@@H](O)CONC(=O)C1=CC=C(F)C(F)=C1NC1=CC=C(I)C=C1F
Molecular Formula
C16H14F3IN2O4
Molecular Weight
482.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C