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DNA-PK-IN-8

CAT: 0931-T61828-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61828-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2823369-81-7
Target
DNA-PK, Others
Related Pathways
PI3K/Akt/mTOR signaling, Others, DNA Damage/DNA Repair
Bioactivity
DNA-PK-IN-8 is a potent, selective, and orally active inhibitor of DNA-dependent protein kinase (DNA-PK) with an IC50 value of 0.8 nM, demonstrating synergistic antiproliferative effects across various cancer cell lines and significantly reducing HL-60 tumor growth when combined with Doxorubicin [1].
Smiles
CN1C=2C(N(CC1=O)C3CCOCC3)=NC(NC4=CN5C(C=C4C)=NC=N5)=NC2
Molecular Formula
C19H22N8O2
Molecular Weight
394.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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