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OTS964

CAT: 0931-T61800-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61800-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1338542-14-5
Target
Others, Apoptosis, CDK, TOPK
Related Pathways
Apoptosis, MAPK, Others, Cell Cycle/Checkpoint
Bioactivity
OTS964 is a potent, orally active compound that operates as a highly selective inhibitor of TOPK with an IC 50 of 28 nM [1]. Additionally, it demonstrates significant inhibitory action against cyclin-dependent kinase CDK11, specifically binding to CDK11B with a K d of 40 nM [2].
Smiles
OC=1C(=C2C3=C(C(=O)NC2=C(C)C1)SC=C3)C4=CC=C([C@H](CN(C)C)C)C=C4
Molecular Formula
C23H24N2O2S
Molecular Weight
392.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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