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BI-D1870

CAT: 0931-T6171-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6171-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
501437-28-1
Target
Autophagy, S6 Kinase
Related Pathways
PI3K/Akt/mTOR signaling, MAPK, Autophagy
Purity
0.9943
Bioactivity
BI-D1870 is a highly specific, blood-brain-permeable, and ATP-competitive inhibitor of the N-terminal AGC kinase domain of RSK, with IC50 values ​​of 31 nM, 24 nM, 18 nM, and 15 nM for RSK1, RSK2, RSK3, and RSK4.
Smiles
CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12
Molecular Formula
C19H23F2N5O2
Molecular Weight
391.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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B2227-50BI-D1870

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