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ThrRS-IN-1

CAT: 0931-T61689-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61689-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2408626-64-0
Target
Others, Antibacterial
Related Pathways
Microbiology/Virology, Others
Bioactivity
ThrRS-IN-1 (Compound 30d) is a potent inhibitor of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica (Se ThrRS), exhibiting an IC50 of 1.4 μM and a Kd of 1.36 μM. It uniquely targets both the tRNA Thr and L-threonine binding sites of ThrRS, demonstrating significant antibacterial activities [1].
Smiles
O=C1C=2C(N=CN1C/C=C/CNC([C@H]([C@@H](C)O)N)=O)=CC(Cl)=C(Cl)C2
Molecular Formula
C16H18Cl2N4O3
Molecular Weight
385.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C