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CCW16

CAT: 0931-T61642-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T61642-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2361138-33-0
Target
ROS, Ligand for E3 Ligase, Ferroptosis
Related Pathways
Apoptosis, PROTAC, Immunology/Inflammation
Purity
0.97
Bioactivity
CCW16 is a covalent E3 ubiquitin ligase RNF4 ligand exhibiting cysteine reactivity, capable of inducing ferroptosis in AML cells by activating ROS signalling. CCW16 may be utilised in synthesising PROTAC degraders such as CCW 28-3.
Smiles
O=C(N(C1=CC=C(OC2=CC=C(OC)C=C2)C=C1)CC=3C=CC=CC3)CCl
Molecular Formula
C22H20ClNO3
Molecular Weight
381.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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