ERK5-IN-4

• Target:

  Others|||ERK

• Related Pathways:

  Others|||MAPK

• Bioactivity:

  ERK5-IN-4 (compound 34b) is a potent and specific inhibitor of extracellular signal-related kinase 5 (ERK5) activity, effectively inhibiting both full-length ERK5 and truncated ERK5 (ERK5 ?TAD) kinase activity in HEK293 cells with IC50 values of 77 nM and 300 nM, respectively [1].

• Smiles:

  C (=O) (C=1C=C (C (NC=2C=NN (C) C2) =O) NC1) C3=C (F) C (Cl) =CC=C3Cl

• Molecular Formula:

  C16H11Cl2FN4O2

• Molecular Weight:

  381.19

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1888305-17-6