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Laquinimod sodium

CAT: 0931-T61607-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61607-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
248282-07-7
Target
Others, NF-κB, Apoptosis
Related Pathways
Others, Apoptosis, NF-κB
Bioactivity
Laquinimod (ABR-215062) sodium is a carboxamide derivative administered orally that serves as a powerful immunomodulator, designed to prevent inflammation and neurodegeneration within the central nervous system. This compound effectively diminishes the activation of astrocytic NF-κB, offering protection against Cuprizone-induced demyelination. It shows promise for the treatment of both relapsing-remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS), in addition to its potential applications in the study of neurodegenerative diseases [1] [2] [3] [4].
Smiles
[Na+].CCN(C(=O)c1c([O-])c2c(Cl)cccc2n(C)c1=O)c1ccccc1
Molecular Formula
C19H16ClN2NaO3
Molecular Weight
378.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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