Laquinimod sodium

• Target :

  Others|||NF-?B|||Apoptosis

• Related Pathways :

  Others|||Apoptosis|||NF-?B

• Bioactivity :

  Laquinimod (ABR-215062) sodium is a carboxamide derivative administered orally that serves as a powerful immunomodulator, designed to prevent inflammation and neurodegeneration within the central nervous system. This compound effectively diminishes the activation of astrocytic NF-?B, offering protection against Cuprizone-induced demyelination. It shows promise for the treatment of both relapsing-remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS), in addition to its potential applications in the study of neurodegenerative diseases [1] [2] [3] [4].

• Smiles :

  [Na+].CCN(C(=O)c1c([O-])c2c(Cl)cccc2n(C)c1=O)c1ccccc1

• Molecular Formula :

  C19H16ClN2NaO3

• Molecular Weight :

  378.79

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  248282-07-7