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Zolunicant

CAT: 0931-T61452-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T61452-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
188125-42-0
Target
Parasite, AChR
Related Pathways
Microbiology/Virology, Neuroscience
Bioactivity
Zolunicant (MM-110) is a potent nicotinic α3β4 receptor inhibitor with an IC50 of 0.90 μM, showing promise in combating addiction. It effectively reduces self-administration of addictive agents such as morphine, cocaine, methamphetamine, nicotine, and ethanol in rat models, indicating its potential as a treatment for various forms of drug abuse [1]. Additionally, Zolunicant exhibits strong leishmanicidal activity against Leishmania amazonensis, expanding its therapeutic prospects [2].
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C(OC)(=O)[C@]12[C@]3([N@](CC(C1)(C[C@@H]3CCOC)[H])CCC4=C2NC=5C4=CC=CC5)[H]
Molecular Formula
C22H28N2O3
Molecular Weight
368.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA2176-1Zolunicant

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