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TRPC3/6-IN-1

CAT: 0931-T61407-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T61407-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
736945-96-3
Target
Others, TRP/TRPV Channel
Related Pathways
Others, Membrane transporter/Ion channel
Bioactivity
TRPC3/6-IN-1 is a highly potent and selective inhibitor that blocks the activity of canonical transient receptor channels TRPC3 and TRPC6, showing significant potency against human isoforms hTRPC3 and hTRPC6 with IC50 values of 1260 nM and 500 nM, respectively. This compound is valuable for research on chronic models of heart failure [1].
Smiles
C(=O)(N1CC=2C(CC1)=CC=CC2)C=3N=C(NC4=CC=C(OC)C=C4)SC3
Molecular Formula
C20H19N3O2S
Molecular Weight
365.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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