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CXCR4 antagonist 8

CAT: 0931-T61363-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61363-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2304750-84-1
Target
Others, CXCR
Related Pathways
GPCR/G Protein, Others, Autophagy, Immunology/Inflammation
Bioactivity
CXCR4 antagonist 8 (Compound 3) is a potent inhibitor of CXCR4, exhibiting an IC50 value of 57 nM in antagonism and effectively inhibiting CXCL12-induced cytosolic calcium increase with an IC50 of 0.24 nM. Additionally, Compound 3 is efficacious in inhibiting CXCL12/CXCR4-mediated cell migration [1].
Smiles
N(CC=1C=C(N=C(C)N1)N2CCN(C)CC2)(C)C=3C4=C(C=CC3)C=CC=N4
Molecular Formula
C21H26N6
Molecular Weight
362.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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