Products for Research Use Only

PTG-0861

CAT: 0931-T61337-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61337-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2494082-34-5
Target
Others, Apoptosis, HDAC
Related Pathways
DNA Damage/DNA Repair, Others, Apoptosis, Chromatin/Epigenetic
Bioactivity
PTG-0861 is a highly specific inhibitor of histone deacetylase 6 (HDAC6), demonstrating an impressive IC50 value of 5.92 nm. This compound effectively triggers apoptosis and holds potential for research pertaining to acute myeloid leukemia, multiple myeloma, and other hematological cancers [1].
Smiles
C(NCC1=CC=C(C(NO)=O)C=C1)(=O)C2=C(F)C(F)=C(F)C(F)=C2F
Molecular Formula
C15H9F5N2O3
Molecular Weight
360.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C