ICG-001

• CAS Number :

  780757-88-2

• Target :

  Epigenetic Reader Domain|||Apoptosis|||Wnt/beta-catenin

• Related Pathways :

  Cytoskeletal Signaling|||Chromatin/Epigenetic|||Stem Cells|||Apoptosis

• Purity :

  >99.99%

• Bioactivity :

  ICG001 is a ?-catenin/TCF-mediated transcription inhibitor that selectively blocks ?-catenin/CBP interaction without interfering with ?-catenin/p300 interaction. It specifically binds to CREB protein with an IC50 of 3 ?M.

• Smiles :

  Oc1ccc(C[C@@H]2N3[C@H](CN(Cc4cccc5ccccc45)C2=O)N(CCC3=O)C(=O)NCc2ccccc2)cc1

• Molecular Formula :

  C33H32N4O4

• Molecular Weight :

  548.63

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C