ICG-001

• Target:

  Epigenetic Reader Domain|||Apoptosis|||Wnt/beta-catenin

• Related Pathways:

  Cytoskeletal Signaling|||Chromatin/Epigenetic|||Stem Cells|||Apoptosis

• Purity:

  >99.99%

• Bioactivity:

  ICG001 is a ?-catenin/TCF-mediated transcription inhibitor that selectively blocks ?-catenin/CBP interaction without interfering with ?-catenin/p300 interaction. It specifically binds to CREB protein with an IC50 of 3 ?M.

• Smiles:

  Oc1ccc (C[C@@H]2N3[C@H] (CN (Cc4cccc5ccccc45) C2=O) N (CCC3=O) C (=O) NCc2ccccc2) cc1

• Molecular Formula:

  C33H32N4O4

• Molecular Weight:

  548.63

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  780757-88-2