L-I-OddU

CAT: 0931-T61080-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T61080-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

207920-87-4

Target

Nucleoside Antimetabolite/Analog, Antifection, DNA/RNA Synthesis, Others

Related Pathways

Cell Cycle/Checkpoint, Microbiology/Virology, Others, DNA Damage/DNA Repair

Bioactivity

L-I-OddU, a potent and selective anti-Epstein-Barr virus (EBV) agent, is a L-5'-halo-dioxolane nucleoside analogue. It demonstrates antiviral activity by effectively suppressing replicative EBV DNA and viral protein synthesis [1] [2]. With an EC 50 value of 0.03 μM, L-I-OddU exhibits high potency against EBV while maintaining low cytotoxicity, as indicated by its CC 50 value of 1000 nM.

Smiles

O=C1N([C@H]2O[C@@H](CO)OC2)C=C(I)C(=O)N1

Molecular Formula

C8H9IN2O5

Molecular Weight

340.07

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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