Milciclib

• CAS Number :

  802539-81-7

• Target :

  Autophagy|||CDK|||Trk receptor

• Related Pathways :

  Autophagy|||Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint

• Purity :

  0.9973

• Bioactivity :

  Milciclib (PHA-848125) (PHA-848125) is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM. It is >3-fold more selective for CDK2 than CDK1, 2, 4, 5, and 7. Phase 2.

• Smiles :

  CNC(=O)c1nn(C)c-2c1C(C)(C)Cc1cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc-21

• Molecular Formula :

  C25H32N8O

• Molecular Weight :

  460.57

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C