NITD-916

• Target:

  Antibacterial|||Antibiotic

• Related Pathways:

  Microbiology/Virology

• Purity:

  0.9978

• Bioactivity:

  NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NADH, preventing access to the fatty acyl substrate-binding pocket.NITD-916 exhibits antituberculosis activity.

• Smiles:

  OC1=C (C2=CC=CC=C2) C (=O) NC (CC3CCC (C) (C) CC3) =C1

• Molecular Formula:

  C20H25NO2

• Molecular Weight:

  311.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1614262-83-7