CP681301

CAT: 0931-T60661Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0931-T60661Size:100 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

865317-32-4

Target

Others, DNA/RNA Synthesis, CDK

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Others

Bioactivity

CP681301 is a potent inhibitor of CDK5 with antiproliferative activity. CP681301 exhibits anti-tumor activity in Drosophila. CP681301 decreases the expression of CD133, OLIG2, SOX2, KI67, pCDK5 protein level in Glioma stem cells (GSCs) . CP681301 reduces self-renewal in mouse glioma xenografts [1].

Smiles

CN(C)c1ccc(CC(=O)Nc2cc([nH]n2)C2CCC2)cc1

Molecular Formula

C17H22N4O

Molecular Weight

298.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C