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Ganciclovir hydrate

CAT: 0931-T60488-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T60488-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1359968-33-4
Target
HSV, Nucleoside Antimetabolite/Analog, Others, Virus Protease, Antibiotic
Related Pathways
Microbiology/Virology, Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
Ganciclovir (BW 759) hydrate is a nucleoside analogue that is an orally active antiviral agent with anti-cytomegalovirus activity. Ganciclovir hydrate is also active against members of the herpes group and some other DNA viruses in vitro. Ganciclovir hydrate inhibits the replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28 in vitro. Ganciclovir hydrate also has an IC 50 of 5.2 μM against feline herpesvirus type-1 (FHV-1) and can diffuse into the brain [1] [2] [3].
Smiles
O.Nc1nc(=O)c2ncn(COC(CO)CO)c2[nH]1
Molecular Formula
C9H15N5O5
Molecular Weight
273.249
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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