DIF-3

• Target:

  GSK-3|||Wnt/beta-catenin|||CDK

• Related Pathways:

  PI3K/Akt/mTOR signaling|||Stem Cells|||Cytoskeletal Signaling|||Cell Cycle/Checkpoint

• Purity:

  0.9957

• Bioactivity:

  DIF-3 is a chemical compound that acts by activating GSK-3? to facilitate the degradation of cyclin D1 and c-Myc, resulting in reduced expression levels of these proteins. In addition, DIF-3 inhibits Wnt/?-catenin signaling pathway-related proteins in DLD-1 cells. This compound exerts a potent antiproliferative effect on the HeLa human cervical cancer cell line by inducing cyclin D1 degradation and inhibiting cyclin D1 mRNA expression [1].

• Smiles:

  CCCCCC(=O)c1c(O)cc(OC)c(Cl)c1O

• Molecular Formula:

  C13H17ClO4

• Molecular Weight:

  272.72

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  113411-17-9