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DYRK1-IN-1

CAT: 0931-T60334-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T60334-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2814486-79-6
Target
Others, DYRK
Related Pathways
Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, Others
Bioactivity
DYRK1-IN-1 is a highly selective and ligand-efficient DYRK1A inhibitor that inhibits DYRK1A phosphorylation activity with an IC50 value of 220 nM. It exhibits good permeability and cellular activity without P-glycoprotein liability, making it suitable for research on central nervous system penetrant DYRK1A chemical probes [1].
Smiles
N(C)(C)C=1N=C(C2=C3N(N=C2)N=CC=C3)C=CN1
Molecular Formula
C12H12N6
Molecular Weight
240.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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