Mirin

• Target:

  ATM/ATR

• Related Pathways:

  DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling

• Purity:

  0.9924

• Bioactivity:

  Mirin is a Mre11-Rad50-Nbs1 (MRN) complex inhibitor that inhibits MRN-dependent ATM activation without affecting ATM protein kinase activity. It also inhibits Mre11-associated exonuclease activity, thereby disrupting DNA double-strand break repair.Mirin induces cell cycle arrest in G1 phase.

• Smiles:

  O=C1N=C(SC1=CC2=CC=C(O)C=C2)N

• Molecular Formula:

  C10H8N2O2S

• Molecular Weight:

  220.25

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  299953-00-7