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RhlR antagonist 1

CAT: 0931-T60249-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T60249-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, Antibacterial
Related Pathways
Others, Microbiology/Virology
Bioactivity
RhlR antagonist 1 is a highly effective antagonist of the RhlR protein, showing an IC50 value of 26 μM. It exhibits selective antagonistic activity against RhlR, with minimal effect on LasR and PqsR. RhlR antagonist 1 strongly inhibits biofilm formation in both static and dynamic environments and reduces the production of virulence factors, such as rhamnolipid and pyocyanin, in P. aeruginosa. These characteristics make RhlR antagonist 1 a valuable tool for the development of molecules that modulate quorum sensing and control P. aeruginosa infections [1].
Molecular Formula
C12H10F2O
Molecular Weight
208.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C