Zosuquidar

CAT: 0931-T6018L-02Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T6018L-02Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

167354-41-8

Target

P-gp

Related Pathways

Neuroscience, Membrane transporter/Ion channel

Purity

0.9999

Bioactivity

Zosuquidar (RS 33295-198) is a potent P-glycoprotein inhibitor with antitumor activity, inhibits tumor growth, significantly inhibits PD-L1 expression by triggering its autophagic degradation, and is used in the study of acute myeloid leukemia.

Smiles

FC1(F)[C@]2([C@@]1(C=3C([C@@H](C=4C2=CC=CC4)N5CCN(C[C@H](COC=6C7=C(C=CC6)N=CC=C7)O)CC5)=CC=CC3)[H])[H]

Molecular Formula

C32H31F2N3O2

Molecular Weight

527.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Zosuquidar

LSM-5782 is a carbopolycyclic compound.

CAS Number	167354-41-8
PubChem CID	3036703
IUPAC Name	(2R)-1-[4-[(2S,4R)-3,3-difluoro-11-tetracyclo[10.4.0.02,4.05,10]hexadeca-1(16),5,7,9,12,14-hexaenyl]piperazin-1-yl]-3-quinolin-5-yloxypropan-2-ol
Molecular Formula	C32H31F2N3O2
Molecular Weight	527.6
XLogP	4.9
Topological Polar Surface Area	48.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	6
Heavy Atom Count	39
Formal Charge	0
Complexity	806

SMILES

C1CN(CCN1C[C@H](COC2=CC=CC3=C2C=CC=N3)O)C4C5=CC=CC=C5[C@H]6[C@H](C6(F)F)C7=CC=CC=C47

InChI

InChI=1S/C32H31F2N3O2/c33-32(34)29-22-7-1-3-9-24(22)31(25-10-4-2-8-23(25)30(29)32)37-17-15-36(16-18-37)19-21(38)20-39-28-13-5-12-27-26(28)11-6-14-35-27/h1-14,21,29-31,38H,15-20H2/t21-,29-,30+,31?/m1/s1

InChIKey

IHOVFYSQUDPMCN-XAKVHENESA-N

Chemical Structure

2D Structure

CAS: 167354-41-8

CID: 3036703

Formula: C32H31F2N3O2

MW: 527.6

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	527.6
XLogP3	4.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	6
Exact Mass	527.23843356
Monoisotopic Mass	527.23843356
Topological Polar Surface Area	48.8 Å²
Heavy Atom Count	39
Formal Charge	0
Complexity	806
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Catalog	Name
HY-15255-01	Zosuquidar
FZ28787-01	Zosuquidar trihydrochloride
MBS8506266-01	LY335979 (Zosuquidar)
A15289-100	Zosuquidar 100mg
A15289-50	Zosuquidar 50mg
S1481-10mg	Zosuquidar 3HCl
HY-50671-01	Zosuquidar (trihydrochloride)
A15289-25	Zosuquidar 25mg

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Chemical Information

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