Linsitinib

CAT: 0931-MF-0013601-01Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0013601-01Size:2 mg
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CAS Number
867160-71-2
Target
IGF-1R
Related Pathways
Tyrosine Kinase/Adaptors
Purity
0.9992
Bioactivity
OSI-906 (Linsitinib (OSI-906) ) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGF-1R stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis.
Smiles
NC=1C=2N(C(=NC2C3=CC4=C(C=C3)C=CC(=N4)C5=CC=CC=C5)[C@H]6C[C@@](C)(O)C6)C=CN1
Molecular Formula
C26H23N5O
Molecular Weight
421.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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