Maraviroc

• Target:

  CCR|||HIV Protease

• Related Pathways:

  Microbiology/Virology|||Immunology/Inflammation|||Proteases/Proteasome|||GPCR/G Protein

• Purity:

  >99.99%

• Bioactivity:

  Maraviroc (Selzentry) is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1? (IC50=3.3 nM), MIP-1? (IC50=7.2 nM) and RANTES (IC50=5.2 nM) .Maraviroc inhibits HIV-1 entry via CCR5 coreceptor interaction.

• Smiles:

  CC(C)c1nnc(C)n1[C@@H]1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1

• Molecular Formula:

  C29H41F2N5O

• Molecular Weight:

  513.67

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  376348-65-1