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Acetylcorynoline

CAT: 0931-T5S2357-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T5S2357-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
18797-80-3
Target
Antifungal
Related Pathways
Microbiology/Virology
Purity
0.9976
Bioactivity
1. Acetylcorynoline (O-Acetylcorynoline) has antifungal, anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3. Acetylcorynoline is potential as a possible antiparkinsonian drug. (1) Significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; (2) Prevents α-synuclein aggregation; (3) Restores food-sensing behavior, and dopamine levels; (4) Prolongs life-span in 6-hydroxydopamine-treated N2 strain. 4. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes.
Smiles
[H][C@]12N(C)Cc3c4OCOc4ccc3[C@@]1(C)[C@H](Cc1cc3OCOc3cc21)OC(C)=O
Molecular Formula
C23H23NO6
Molecular Weight
409.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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