Products for Research Use Only

Loureirin A

CAT: 0931-T5S0896-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T5S0896-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
119425-89-7
Target
PI3K, Akt
Related Pathways
Cytoskeletal Signaling, PI3K/Akt/mTOR signaling
Purity
0.9997
Bioactivity
Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related peptide (CRP), ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs) -seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4, inhibiting the synthesis and secretion of α- SMA, TGF- β1and the proliferation of HSCs.
Smiles
COc1ccc(CCC(=O)c2ccc(O)cc2)c(OC)c1
Molecular Formula
C17H18O4
Molecular Weight
286.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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