Products for Research Use Only

Oleandrin

CAT: 0931-T5S0890-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T5S0890-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
465-16-7
Target
Potassium Channel, Apoptosis, ATPase, Sodium Channel
Related Pathways
Membrane transporter/Ion channel, Apoptosis
Purity
0.9994
Bioactivity
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. 3. Oleandrin has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM), causes an autophagic cell death and altered ERK phosphorylation in undifferentiated.
Smiles
[H][C@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@H]([C@H](C[C@]34O)OC(C)=O)C3=CC(=O)OC3)[C@@]1(C)CC[C@@H](C2)O[C@H]1C[C@H](OC)[C@@H](O)[C@H](C)O1
Molecular Formula
C32H48O9
Molecular Weight
576.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C