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Atractylenolide I

CAT: 0931-T5S0167-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T5S0167-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
73069-13-3
Target
IL Receptor, STAT, JAK, TLR, TNF
Related Pathways
Apoptosis, Stem Cells, Angiogenesis, Immunology/Inflammation, Chromatin/Epigenetic, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Purity
0.9992
Bioactivity
1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide-I significantly sensitizes the response of MyD88 (+) EOC cells to paclitaxel by blocking MD-2-mediated TLR4/MyD88 signaling.
Smiles
CC1=C2C[C@H]3C(=C)CCC[C@]3(C)C=C2OC1=O
Molecular Formula
C15H18O2
Molecular Weight
230.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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