BI-3802

• Target :

  Bcl-2 Family|||Molecular Glues|||Bcl-6

• Related Pathways :

  PROTAC|||Apoptosis|||Immunology/Inflammation

• Purity :

  0.9948

• Bioactivity :

  BI-3802, a highly potent BCL6 degrader, targets and inhibits the Bric-à-brac (BTB) domain of BCL6, exhibiting an IC50 value of ?3 nM. It induces polymerization of BCL6 and facilitates its degradation in a manner dependent on the E3 ligase SIAH1, demonstrating notable antitumor activity[1][2].

• Smiles :

  CNC(=O)COc1cc2cc(Nc3nc(ncc3Cl)N3C[C@@H](C)C[C@@H](C)C3)ccc2n(C)c1=O

• Molecular Formula :

  C24H29ClN6O3

• Molecular Weight :

  484.98

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2166387-65-9