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BI-3802

CAT: 0931-T5408-01Size: 1 mgDry Ice: NoHazardous: No
CAT#: T5408-01Size: 1 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2166387-65-9
Target
Bcl-2 Family|||Molecular Glues|||Bcl-6
Related Pathways
PROTAC|||Apoptosis|||Immunology/Inflammation
Purity
0.9948
Bioactivity
BI-3802, a highly potent BCL6 degrader, targets and inhibits the Bric-à-brac (BTB) domain of BCL6, exhibiting an IC50 value of ?3 nM. It induces polymerization of BCL6 and facilitates its degradation in a manner dependent on the E3 ligase SIAH1, demonstrating notable antitumor activity[1][2].
Smiles
CNC(=O)COc1cc2cc(Nc3nc(ncc3Cl)N3C[C@@H](C)C[C@@H](C)C3)ccc2n(C)c1=O
Molecular Formula
C24H29ClN6O3
Molecular Weight
484.98
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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