BI-3802

• Target:

  Bcl-2 Family|||Molecular Glues|||Bcl-6

• Related Pathways:

  PROTAC|||Apoptosis|||Immunology/Inflammation

• Purity:

  0.9948

• Bioactivity:

  BI-3802, a highly potent BCL6 degrader, targets and inhibits the Bric-à-brac (BTB) domain of BCL6, exhibiting an IC50 value of ?3 nM. It induces polymerization of BCL6 and facilitates its degradation in a manner dependent on the E3 ligase SIAH1, demonstrating notable antitumor activity[1][2].

• Smiles:

  CNC(=O)COc1cc2cc(Nc3nc(ncc3Cl)N3C[C@@H](C)C[C@@H](C)C3)ccc2n(C)c1=O

• Molecular Formula:

  C24H29ClN6O3

• Molecular Weight:

  484.98

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2166387-65-9