Sugammadex

CAT: 0931-T5326LSize: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T5326LSize:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

343306-71-8

Target

Others

Related Pathways

Others

Bioactivity

Sugammadex is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA) . Sugammadex is a modified γ-cyclodextrin, with a lipophilic core and a hydrophilic periphery. This gamma cyclodextrin has been modified from its natural state by placing eight carboxyl thio ether groups at the sixth carbon positions. These extensions extend the cavity size allowing greater encapsulation of the rocuronium molecule. These negatively charged extensions electrostatically bind to the quaternary nitrogen of the target as well as contribute to the aqueous nature of the cyclodextrin.

Smiles

O[C@@H]1[C@@H](O)[C@@H]2O[C@H]3O[C@H](CSCCC(O)=O)[C@@H](O[C@H]4O[C@H](CSCCC(O)=O)[C@@H](O[C@H]5O[C@H](CSCCC(O)=O)[C@@H](O[C@H]6O[C@H](CSCCC(O)=O)[C@@H](O[C@H]7OC(CSCCC(O)=O)[C@@H](O[C@H]8O[C@H](CSCCC(O)=O)[C@@H](O[C@H]9OC(CSCCC(O)=O)[C@@H](O[C@H]1OC2CSCCC(O)=O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O

Molecular Formula

C72H112O48S8

Molecular Weight

2002.15

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Alternative Products

Catalog	Name
RM-S075426-01	Sugammadex-Ss- Sugammadex (Dimer)
RM-S075436-01	Sugammadex-S-Sugammadex Dimer
MBS5785951	Sugammadex
RM-S075465-01	Mono Hydroxy Of Sugammadex; Monohydroxy Sugammadex
FS157329-01	Sugammadex sodium
HY-B0079-01	Sugammadex (sodium)
AR-S02202-01	Monohydroxy Sugammadex
CS-O-49187	Sugammadex octasulfoxide

Sugammadex

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