Cridanimod sodium

• Target:

  Others|||IFNAR

• Related Pathways:

  Others|||Immunology/Inflammation

• Bioactivity:

  Cridanimod can increase progesterone receptor (PR) expression, with potential antineoplastic adjuvant activity. Cridanimod is able to induce the expression of PR in endometrial cancer. In combination with a progestin, cancer cells could be eradicated through increased PR-mediated signaling, leading to an inhibition of luteinizing hormone release from the pituitary gland, via a negative feedback mechanism, and, eventually, an inhibition of estrogen released from the ovaries.

• Smiles:

  [Na+].[O-]C(=O)CN1C2=C(C=CC=C2)C(=O)C2=C1C=CC=C2

• Molecular Formula:

  C15H11NNaO3

• Molecular Weight:

  276.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  58880-43-6