Cridanimod sodium

CAT: 0931-T5317L-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T5317L-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

58880-43-6

Target

Others, IFNAR

Related Pathways

Others, Immunology/Inflammation

Bioactivity

Cridanimod can increase progesterone receptor (PR) expression, with potential antineoplastic adjuvant activity. Cridanimod is able to induce the expression of PR in endometrial cancer. In combination with a progestin, cancer cells could be eradicated through increased PR-mediated signaling, leading to an inhibition of luteinizing hormone release from the pituitary gland, via a negative feedback mechanism, and, eventually, an inhibition of estrogen released from the ovaries.

Smiles

[Na+].[O-]C(=O)CN1C2=C(C=CC=C2)C(=O)C2=C1C=CC=C2

Molecular Formula

C15H11NNaO3

Molecular Weight

276.24

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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