Ammonium formate

CAT: 0931-MF-0045881Size: 10 gDry Ice: NoHazardous: No
CAT#:0931-MF-0045881Size:10 g
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CAS Number
540-69-2
Target
Others|||Endogenous Metabolite
Related Pathways
Metabolism|||Others
Purity
0.98
Bioactivity
Ammonium formate (Formic acid ammonium salt) is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron transport and energy production by inhibiting cytochrome oxidase activity, the terminal electron acceptor of the electron transport chain. Cell death from cytochrome oxidase inhibition by formate is believed to result partly from depletion of ATP, reducing energy concentrations so that essential cell functions cannot be maintained. Furthermore, inhibition of cytochrome oxidase by formate may also cause cell death by increased production of cytotoxic reactive oxygen species (ROS) secondary to the blockade of the electron transport chain.
Smiles
[NH4+].[O-]C=O
Molecular Formula
CH5NO2
Molecular Weight
63.06
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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