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PXT-012253

CAT: 0804-HY-167899Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-167899Size:1 Each
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Description
PXT-012253 is a positron emission tomography (PET) ligand for mGluR4, as it binds to an allosteric site on mGluR4. PXT-012253 can be utilized in researches related to Parkinson's disease and levodopa-induced dyskinesia[1].
CAS Number
1835647-08-9
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pxt-012253.html
Smiles
O=C(C1=NC=CC=C1)NC2=CC=C(C(SC)=C2)Cl
Molecular Formula
C13H11ClN2OS
Molecular Weight
278.76
References & Citations
[1]Takano A, et al. Characterization of [11C]PXT012253 as a PET Radioligand for mGlu4 Allosteric Modulators in Nonhuman Primates. Mol Imaging Biol. 2019 Jun;21 (3) :500-508.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR4

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