Cinnamaldehyde

• Target :

  HIF

• Related Pathways :

  Angiogenesis|||Chromatin/Epigenetic

• Purity :

  0.9707

• Bioactivity :

  1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the expression of miR-27a. 4. Cinnamaldehyde induces the generation of reactive oxygen species and exerts vasodilator and anticancer effects. 5. Cinnamaldehyde appears to be a promising candidate as an adjuvant in combination therapy with 5-fluorouracil (5-FU) and oxaliplatin (OXA), two chemotherapeutic agents used in CRC treatment. The possible mechanisms of its action may involve the regulation of drugmetabolizing genes. 6. Cinnamaldehyde plays a certain role in inhibiting the occurrence and progression of melanoma and its action mechanism may be manifested by inhibiting expression of VEGF and HIF-?, thus blood vessel simulation and formation of new blood vessels of melanoma cells, and growth of tumors accordingly.

• Smiles :

  O=CC=CC=1C=CC=CC1

• Molecular Formula :

  C9H8O

• Molecular Weight :

  132.16

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  104-55-2