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Demethyleneberberine

CAT: 0931-T4S0800-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T4S0800-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
25459-91-0
Target
AMPK, NOS, Cytochromes P450, NF-κB, HIF
Related Pathways
PI3K/Akt/mTOR signaling, Metabolism, Angiogenesis, Chromatin/Epigenetic, Immunology/Inflammation, NF-κB
Purity
0.9918
Bioactivity
Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.Demethyleneberberine suppresses CYP2E1, hypoxia inducible factor α, and inducible nitric oxide synthase, which contributes to oxidative stress and restored sirtuin 1/AMP-activated protein kinase/peroxisome proliferator-activated receptor-γ coactivator-1α pathway-associated fatty acid oxidation in chronic ethanol-fed mice.
Smiles
OC=1C=C2C=3[N+](=CC=4C(C3)=CC=C(OC)C4OC)CCC2=CC1O
Molecular Formula
C19H18NO4
Molecular Weight
324.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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FD74150-01Demethyleneberberine
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A22273-10Demethyleneberberine 10mg
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